PROMIFEN (CLOMIPHENE CITRATE – CLOMID)
What is Promifen all about ?
Clomiphene is used to induce ovulation (egg production) in women who do not produce ova (eggs) but wish to become pregnant (infertility). Clomiphene is in a class of medications called ovulatory stimulants. It works similarly to estrogen, a female hormone that causes eggs to develop in the ovaries and be released.
Clomiphene is also sometimes used to treat male infertility, menstrual abnormalities, fibrocystic breasts, and persistent breast milk production. Talk to your doctor about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Before taking clomiphene,
- tell your doctor and pharmacist if you are allergic to clomiphene or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.
- tell your doctor if you have or have ever had liver disease, ovarian cysts (except those from polycystic ovary syndrome), uterine fibroids, abnormal vaginal bleeding, a pituitary tumor, or thyroid or adrenal disease.
- tell your doctor if you are pregnant or breast-feeding. If you become pregnant while taking clomiphene, call your doctor immediately.
- you should know that clomiphene may cause blurred vision. Do not drive a car or operate machinery, especially in poor lighting, until you know how this medication affects you.
- you should know that clomiphene increases the chance of multiple pregnancy (twins or more). Talk to your doctor about the risks of multiple pregnancy.
Promifen (Clomiphene Citrate), even though it is classified being an anti-Estrogen, is definitely used to the remedy of woman infertility ensuing from ovulation failure (anovulatory infertility). Despite the fact that Promifen (Clomiphene Citrate) is a really close relative to Nolvadex with both belonging on the SERM group of medication, Promifen (Clomiphene Citrate) In point of fact operates at a much poorer efficiency when compared to Nolvadex with regard to its Estrogen antagonistic activity in breast tissue. This is often to say that it is a weaker Estrogen blocker in breast tissue, in which Nolvadex is much better suited for this job.
One particular pill of Promifen fifty mg need to be administered daily for five times beginning about the fifth day of the menstrual cycle. If ovulation isn’t going to look to have happened, a 2nd course of two tablets of Promifen fifty every day (in a single dose) for 5 days ought to be offered ranging from the fifth day of the following cycle.
It has by now been proven that Promifen (Clomiphene Citrate), remaining a SERM, isn’t going to reduce circulating Estrogen levels in the human body, but as an alternative serves to occupy the receptor sites in breast tissue to ensure Estrogen itself can’t bind to these receptors due to Promifen (Clomiphene Citrate)’s more robust binding toughness to it. In layman’s terms, Promifen (Clomiphene Citrate) basically acts being a ‘pretend’ Estrogen that acts being a placeholder within the receptor internet sites in breast tissue.
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